Difficulty: Medium
Average Score: 81%
Simulated
Why must the nurse instruct a patient receiving metformin (Glucophage XL) to avoid crushing or chewing the medication?
Correct answer
D
Rationale
The correct answer is D: The effect of the medication may be changed. Metformin is an extended-release medication designed to release slowly in the body. Crushing or chewing it would disrupt this mechanism, leading to a rapid release of the drug and potentially altering its effectiveness. Therefore, the nurse must instruct the patient to swallow the medication whole to ensure proper absorption and therapeutic effect.
Choice A is incorrect because choking is not the primary reason for avoiding crushing or chewing metformin. Choice B is incorrect as crushing or chewing would not cause blood glucose levels to rise rapidly. Choice C is incorrect as oral mucosal irritation is not the main concern with metformin.
Choice A is incorrect because choking is not the primary reason for avoiding crushing or chewing metformin. Choice B is incorrect as crushing or chewing would not cause blood glucose levels to rise rapidly. Choice C is incorrect as oral mucosal irritation is not the main concern with metformin.