Which statement best describes Paracetamol├óÔé¼Ôäós antipyretic mechanism?

Paracetamol (acetaminophen) exerts its antipyretic effect primarily by inhibiting prostaglandin synthesis within the hypothalamic thermoregulatory center. This lowers the set-point temperature, leading to heat dissipation via vasodilation and sweating. Its action is largely central, distinguishing it from NSAIDs, which act peripherally. The reduction in body temperature from 39.2°C to 37.5°C illustrates effective normalization through hypothalamic control rather than anti-inflammatory effects.