Which mechanism best explains the improvement after Salbutamol administration?

Salbutamol (albuterol) acts as a short-acting beta-2 adrenergic receptor agonist, leading to relaxation of bronchial smooth muscle and subsequent bronchodilation. The decrease in respiratory rate and relief of wheezing demonstrate effective airway opening. It does not work by blocking muscarinic receptors or inhibiting cytokines directly. Its selective beta-2 stimulation enhances airflow, making it the first-line treatment for acute asthma exacerbations and chronic obstructive airway diseases.