Difficulty: Medium
Average Score: 76%
Simulated
Which is the pathophysiological basis for Parkinson's disease?
Correct answer
A
Rationale
Parkinson's disease results from degeneration of dopamine-producing neurons in the substantia nigra, leading to dopamine deficiency in the basal ganglia. This causes bradykinesia, rigidity, and tremor. Myelin disruption is seen in multiple sclerosis. Serotonin imbalance is linked to mood disorders. Acetylcholine decrease is more relevant in Alzheimer's.