Difficulty: Medium
Average Score: 73%
Simulated
What is the mechanism of action used by cephalosporins in the treatment of bacterial infections?
Correct answer
C
Rationale
Cephalosporins exert their mechanism of action by inhibiting cell wall synthesis in bacteria. This is achieved by binding to penicillin-binding proteins (PBPs) and disrupting the cross-linking of peptidoglycans in the bacterial cell wall. This weakens the cell wall, leading to bacterial cell lysis and eventual death. In contrast, choice A (Inhibition of protein synthesis) is typically associated with antibiotics like macrolides and aminoglycosides. Choice B (Inhibition of DNA replication) is a mechanism of action for antibiotics like fluoroquinolones. Choice D (Inhibition of folic acid synthesis) is a mechanism seen in antibiotics like sulfonamides. Overall, the correct answer, choice C, is specific to cephalosporins due to their ability to disrupt cell wall synthesis.