Difficulty: Medium
Average Score: 90%
Simulated
The nurse is reviewing the medication orders for a client who will be receiving aminoglycoside therapy. Which other medication or medication class, if ordered, would be a potential interaction concern?
Correct answer
C
Rationale
Rationale: Loop diuretics can increase the risk of aminoglycoside-induced nephrotoxicity due to additive effects on kidney function. Loop diuretics promote diuresis by inhibiting sodium reabsorption in the loop of Henle, leading to electrolyte imbalances and potential renal impairment when combined with aminoglycosides. Calcium channel blockers, proton pump inhibitors, and lithium do not typically interact significantly with aminoglycosides, making them less concerning in this scenario.