Difficulty: Medium
Average Score: 95%
Simulated
The development of atherosclerosis is a process of sequential events. Arrange the pathophysiological events in order of occurrence. Place the first event on top, and the last on the bottom.
Correct answer
A,D,C,E,B
Rationale
Atherosclerosis begins with endothelial injury and inflammation (A), followed by macrophage LDL uptake forming foam cells (D). Foam cells release growth factors (C), prompting smooth muscle growth over fatty streaks, forming fibrous plaques (E). Plaques narrow vessels, causing ischemia (B).