Difficulty: Medium
Average Score: 94%
Simulated
A nurse is preparing to administer diphenhydramine to a client who is to receive a blood transfusion. The nurse should explain that the purpose diphenhydramine is to prevent which of the following manifestations of a transfusion reaction?
Correct answer
D
Rationale
The correct answer is D: Urticaria. Diphenhydramine is an antihistamine that helps prevent allergic reactions, such as urticaria (hives), during a blood transfusion. Histamine release can lead to urticaria, so administering diphenhydramine before the transfusion can help block histamine receptors and reduce the risk of developing hives. Low-back pain (A), fever (B), and dyspnea (C) are not typically prevented by diphenhydramine as they are not directly related to histamine release or allergic reactions during transfusions.