A nurse is preparing to administer amphotericin B lipid complex via intermittent IV bolus to a client who has infective endocarditis. Which of the following actions should the nurse take?

The correct answer is B: Prime the tubing with 0.9% sodium chloride. This is important to prevent amphotericin B lipid complex from interacting with other medications or substances in the tubing, which could result in precipitation or inactivation. Using a gravity flow set (A) is not recommended as it may not provide accurate control over the rate of infusion. Discarding the medication if it is yellow (C) is incorrect because amphotericin B lipid complex is naturally yellow in color. Administering the medication over 2 hr (D) is also incorrect as the recommended infusion time is typically longer.