A nurse is monitoring a client who is receiving a transfusion of packed RBCs. The nurse should identify which of the following findings as an indication of a febrile nonhemolytic reaction?

The correct answer is D: Chills. Febrile nonhemolytic reaction during a blood transfusion is characterized by the sudden onset of chills and fever. This occurs due to the recipient's immune system reacting to donor leukocytes. Dyspnea (A) is more indicative of acute hemolytic reaction. Urticaria (B) is associated with allergic reactions. Vomiting (C) is not typically a sign of a febrile reaction. In summary, chills are the most specific finding for a febrile nonhemolytic reaction during a blood transfusion.