A nurse is monitoring a client who has a head injury and is receiving mannitol 25% via IV infusion. The nurse should identify which of the following as an adverse effect of the medication and report to the provider?

The correct answer is B: Crackles on auscultation. Mannitol can cause fluid overload leading to pulmonary edema, which can manifest as crackles on auscultation. This is a concerning adverse effect that should be reported to the provider promptly to prevent respiratory compromise. A: Glasgow coma scale of 15 is normal, C: Increase in urinary output is an expected effect of mannitol, and D: Intracranial pressure reading of 12mm is within the normal range for a client with a head injury receiving mannitol.