Difficulty: Medium
Average Score: 86%
Simulated
A nurse is educating a client who is prescribed clozapine. Which of the following findings should the nurse identify as consistent with agranulocytosis and instruct the client to monitor?
Correct answer
A
Rationale
The correct answer is A: Sore throat and muscle aches. Agranulocytosis is a severe side effect of clozapine characterized by a significant decrease in white blood cells, particularly granulocytes. This condition can lead to increased susceptibility to infections. Sore throat and muscle aches are early signs of infection that the nurse should instruct the client to monitor for. Choice B, severe restlessness, is not typically associated with agranulocytosis. Choice C, increased anxiety and suicidal ideations, are more indicative of mental health issues rather than agranulocytosis. Choice D, respiratory depression and a comatose state, are not typical manifestations of agranulocytosis.