A nurse is discussing adverse reactions to pain medications in older adult clients with a newly licensed nurse. Which of the following findings should the nurse include as risk factors for an adverse drug reaction? (Select all that apply.)

The correct answer includes polypharmacy, multiple health problems, decreased percentage of body fat, and decreased renal function as risk factors for adverse drug reactions in older adults. Polypharmacy increases the likelihood of drug interactions and side effects. Multiple health problems can complicate medication management. Decreased body fat can lead to higher medication concentrations in the bloodstream, increasing the risk of toxicity. Decreased renal function can impair drug clearance, prolonging drug effects. Choices C, F, and G are incorrect because an increased rate of absorption is not a typical risk factor for adverse drug reactions in older adults, and no information is provided for choices F and G.