Difficulty: Medium
Average Score: 75%
Simulated
A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Correct answer
C
Rationale
The correct answer is C: Isosorbide. Sildenafil is contraindicated with nitrates like isosorbide due to the risk of severe hypotension. Nitrates and sildenafil both cause vasodilation, leading to a significant drop in blood pressure when taken together. Choices A, B, and D do not have significant interactions with sildenafil. Choice E, F, and G are irrelevant.