A nurse is caring for a client who is postoperative following a cholecystectomy. Which of the following positions should the nurse place the client in to promote comfort?

The correct answer is C: Semi-Fowler's position. This position is ideal post-cholecystectomy to promote comfort as it helps reduce tension on the abdominal incision, decreases pressure on the diaphragm, and facilitates breathing. Elevating the head of the bed also aids in preventing aspiration and promotes optimal digestion. Choice A (Supine with legs elevated) may increase abdominal pressure and discomfort. Choice B (Left lateral with knees bent) may not provide adequate support for the incision site. Choice D (Prone with a pillow under the abdomen) is contraindicated as it can increase pressure on the surgical site.