A nurse is caring for a client who has major depressive disorder. Which of the following findings should the nurse expect?

The correct answer is B: Feelings of worthlessness. In major depressive disorder, individuals often experience persistent feelings of worthlessness, guilt, or self-blame. This is a key symptom of depression as outlined in the DSM-5 criteria. Increased energy levels (A) and improved concentration (C) are not typical findings in major depressive disorder, as individuals commonly report fatigue and difficulty concentrating. Elevated mood (D) is more characteristic of manic episodes in bipolar disorder rather than major depressive disorder.