A client with chronic osteoarthritis is reporting knee pain. Which pathophysiological process is contributing to the pain?

D Joint destruction happens due to an autoimmune inflammation involving IgG response to an antigen. B Inflammation is caused by immune complex and autoantibody deposition in connective tissue. A Inflammation results from deposition of crystals in the synovial space of joints producing irritation. C Joint inflammation occurs when chondrocyte injury destroys joint cartilage, producing osteophytes.