A client has prescriptions for albuterol (Proventil HFA) and salmeterol (Serevent). Which instruction should the nurse provide for this client?

The correct answer is A: Take albuterol first. Albuterol is a short-acting beta-agonist used for quick relief of asthma symptoms, while salmeterol is a long-acting beta-agonist for maintenance treatment. Albuterol should be taken first to provide immediate relief of symptoms, followed by salmeterol for long-term control. Taking them together may reduce the effectiveness of both medications. Option B is incorrect because the order of administration does matter in this case. Option C is incorrect as they can be taken together, but albuterol should be taken first. Option D is incorrect as salmeterol should be taken after albuterol.