Which laboratory method is most useful to separate genomic DNA fragments by size?

Electrophoresis is the most suitable laboratory method for separating genomic DNA fragments by size. It works by subjecting DNA fragments to an electric field, causing them to migrate through a gel matrix based on size differences. Smaller fragments move faster and travel farther than larger ones, allowing for separation and analysis based on size. Titration is a technique used to determine the concentration of a solution, not to separate DNA fragments by size. Spectrophotometry is used to measure the amount of light absorbed by a substance at different wavelengths, not for DNA fragment size separation. Filtration is a method used to separate solid particles from a liquid or gas by passing it through a filter medium, not for separating DNA fragments by size.